DPCstruct | MC22058

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)385 ± 111 aa
Standard deviation of domain lengths110.86
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score74.78
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)30.97
Pfam Score91.81
Assigned Pfam label(s) PF20235- PF12274

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A368SCI7 2-375 PRRARRLLTSYFRYLTAWEALYYLRRSRADLLVAVHLVEEDHATRGFALDHPTTKVALACAARSAMHPRPDAFMSASVSLASRRRQM…
A0A453JKZ2 59-391 SDVCLGVCVGLLDPVSNIIASTLLAAAEAPVDTGGPTAVDGPRLRDMERRSLDGLVAFLTCFFPYLADWEAVRYLLLAEADPIVAAR…
R7VZ06 2-413 None
Q5Z8Y1 214-476 None
B8BGG6 91-332 None
A0A0A9PJM5 34-443 None
A0A835A1L8 9-490 None
A0A835A7P4 31-322 None
A0A3L6TC23 2-282 None
A0A835AA50 16-414 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.