DPCstruct | MC22054

Metacluster Properties and Pfam Annotations

Number of structural domains1545
Mean domain length (aa)225 ± 53 aa
Standard deviation of domain lengths53.11
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.19
Pfam Score83.21
Assigned Pfam label(s) PF03105- PF05216- PF04987- PF17830- PF04770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A498ILS0 26-170 None
A3AEZ0 6-256 None
A0A7J8YEJ4 18-185 None
A0A7J8Y3L8 2-209 None
A0A2I0ACW3 1-200 None
A0A2I0A0C8 64-298 None
A0A2G3BK73 266-467 None
A0A2Z6P162 18-182 None
A0A2Z6NYH0 15-210 None
A0A2Z6NX60 302-547 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.