DPCstruct | MC22054

Metacluster Properties and Pfam Annotations

Number of structural domains1545
Mean domain length (aa)225 ± 53 aa
Standard deviation of domain lengths53.11
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.19
Pfam Score83.21
Assigned Pfam label(s) PF03105- PF05216- PF04987- PF17830- PF04770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6LWH1 13-227 None
A0A2Z6LU22 4-178 None
A0A2Z6LS49 122-368 None
A0A2Z6LRM2 70-285 None
A0A835LET4 9-151 None
A0A835IRF1 173-387 None
A0A835III8 30-224 None
A0A2Z6M8V2 1-209 None
A0A3R6VXZ5 3-328 None
B9FE14 446-711 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.