DPCstruct | MC22054

Metacluster Properties and Pfam Annotations

Number of structural domains1545
Mean domain length (aa)225 ± 53 aa
Standard deviation of domain lengths53.11
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score74.81
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)18.19
Pfam Score83.21
Assigned Pfam label(s) PF03105- PF05216- PF04987- PF17830- PF04770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3P6C524 7-135 DRLPTRSRLAAWGLPIAPTCPLCSRYDETRDHLMLSCEYSYEVWSGVMRRCHPPPSRIASWSELLSWIRSSPSKRLTLLRKIAAQTV…
A0A2N9EZU7 51-292 LKEGYPDLFRIARDKEALVVDHMCFENGVVSWVLNFTRSAQDWELDSIAAFLKLLYSSSAKGQGEDRLCWQGSASGAFQVKAYYKAL…
A0A438DVL1 164-389 None
K3X6Y9 29-237 None
A0A438DU34 128-409 None
A0A438DTJ4 50-298 None
A0A438DRP3 237-511 None
A0A438DHF4 292-502 None
A0A438DH28 815-1105 None
A0A438DE88 792-1036 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.