DPCstruct | MC22049

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)70 ± 6 aa
Standard deviation of domain lengths5.62
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.54
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)41.24
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G2E0L8 10-78 AELIPSDYASWRYCIEVKCGLALEPDFLRARIAVLSDPGHEETQRFARLYGDTHLNRILAWFRQAAAEA
A0A171KPI7 1-71 MPALIPRTYEQWHHCIVRECGIPLTTAFIAQRLATWRNPEAEETRRFRKRYGDAHWQAILAWFEQAAQEAQ
A0A1Q3ZGF4 1-61 None
A0A2W4VEB3 6-82 None
A0A4Q5L505 2-70 None
A0A3D4S290 7-83 None
A0A517P287 4-72 None
F4CFI5 21-84 None
A0A1H2NEW7 3-61 None
A0A3P8KIN5 1-76 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.