DPCstruct | MC22038

Metacluster Properties and Pfam Annotations

Number of structural domains284
Mean domain length (aa)222 ± 52 aa
Standard deviation of domain lengths51.73
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score91.06
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.55
Pfam Score98.57
Assigned Pfam label(s) CL0292- CL0318

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V8I8I2 144-460 FSRRNAPSLLYVRYVPRRHFYQDDDALAPAPFGGLFSDGRADTLAEQLRGPLFDPDEMNNASPAALTRKIGGTALGAALAERFGPSV…
A0A524KMC4 40-235 LKTGPFTADGRATTLREQALEAAMLHLLDGAADRPGERLPTAGELDAIVAFEETMREPETGGLGLNLKTAKAREGHKLFFGAARCTA…
A0A7V9BUM2 2-158 None
A0A3D4BVU9 14-190 None
A0A2H5A2B6 95-353 None
A0A2E0WMN0 199-362 None
A0A2G2M050 207-469 None
A0A517YDJ4 559-766 None
A0A534HNR9 333-571 None
A0A7V3DXK3 442-616 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.