DPCstruct | MC22032

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)148 ± 9 aa
Standard deviation of domain lengths8.51
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score83.23
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)59.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377WK71 1-156 MPPVWRRHPQWRLPVDDGLVSQVRTRLIRQMGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQ…
A0A2X1QC18 178-322 LASHPQWRLPVDDGLVSQVRTRLIRQLGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQP…
A0A2X3IM73 2-137 None
A0A4Q4WP38 3-128 None
A0A377XBL2 392-542 None
A0A377VCM9 1-157 None
A0A530M978 359-512 None
A0A0Q3E0W1 294-443 None
A0A377TUU9 248-399 None
K8CAT8 163-312 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.