DPCstruct | MC22031

Metacluster Properties and Pfam Annotations

Number of structural domains552
Mean domain length (aa)114 ± 17 aa
Standard deviation of domain lengths16.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.29
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)15.11
Pfam Score94.03
Assigned Pfam label(s) CL0257- CL0123- CL0020- CL0310- CL0311

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A6EQY7 328-443 None
A0A183AMF0 251-386 None
A0A813C7B5 247-372 None
A0A0H3FZI0 37-165 None
A0A7J7B1I8 7-116 None
A0A341CSA0 197-307 None
A0A3Q2YU65 7-118 None
A0A5C9EZB3 538-658 None
A0A7H0H8A0 2-136 None
A0A120J3K4 72-208 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.