DPCstruct | MC22026

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)81 ± 6 aa
Standard deviation of domain lengths6.26
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score87.86
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.90
Mean intra-cluster sequence similarity (%)60.67
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A377VTK8 1-87 MPFCEAVHNVMTNTLLPPDSKGVMVALRPAPGLRVEQALTLCKPNRMGDIMTIGNNRLVLFLSFCRINDLDTALNHIFPLPTGDIFF
A0A377US72 52-136 FCEAVHNVMTNTLLPPDSKGVMVALRPAPGLRVEQALTLCKPNRMGDIMTIGNNRLVLFLSFCRINDLDTALNHIFPLPTGDIFS
A0A376TXK0 191-275 None
A0A090T1R1 113-188 None
W1EVG6 278-362 None
K8BEP8 75-159 None
B8L0X4 39-116 None
A0A2X2T2X6 75-159 None
A0A485BBS0 1-77 None
A0A1C2K9G8 3-76 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.