DPCstruct | MC22025

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)150 ± 26 aa
Standard deviation of domain lengths25.66
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.12
Mean fraction of residues predicted as intrinsically disordered0.90
Mean length-normalized TM-Score0.38
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.98
Pfam Score66.67
Assigned Pfam label(s) CL0123- PF08364

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A485D938 1-108 MQGFANRADDSVTAQEKQTLLTHLNREHGSAPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQRE…
A0A377WPW6 1-153 MTDVTIKALASEIQTSVDRLIQQFADAGIRKSADDSVTSQEKQTLLTHLNREHGSAPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVR…
A0A090SZZ5 2-105 None
D1KAN3 1-147 None
A0A6L7KWK2 1-148 None
A0A7R9QVA2 1-153 None
A0A2X2BPY0 2-133 None
A0A378AGR7 1-153 None
A3RXC9 1-174 None
C0B0G1 15-128 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.