DPCstruct | MC22021

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)54 ± 3 aa
Standard deviation of domain lengths2.83
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score89.28
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.93
Mean intra-cluster local Distance Difference Test score0.95
Mean intra-cluster sequence similarity (%)55.51
Pfam Score100.00
Assigned Pfam label(s) CL0178

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X1PX27 1-55 MTKQILLVSQREADLEEPTPEDLFDVGTIANIIQLLKLPDGTVKVLVEGQNRAKN
A0A377UYB8 1-61 MDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGAAACSHFCAV
S7V8Y3 68-121 None
W9T9W7 514-565 None
A0A2A2M5J5 1-54 None
A0A7H4NPR6 45-99 None
A0A0H4T1T6 59-109 None
A0A183BXS7 464-515 None
A0A7C6WGZ5 44-95 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.