DPCstruct | MC22015

Metacluster Properties and Pfam Annotations

Number of structural domains258
Mean domain length (aa)99 ± 13 aa
Standard deviation of domain lengths13.30
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.66
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)26.67
Pfam Score86.28
Assigned Pfam label(s) CL0023- CL0437- CL0329- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D6GUK6 318-418 None
A8PXE5 555-658 None
A0A0D1JF13 2-78 None
A0A813AFW7 386-473 None
A0A812QE26 646-717 None
A0A423WPX6 411-516 None
A0A0D2IXY9 123-219 None
A0A1X6NPL4 139-255 None
A0A7R8VLK9 735-836 None
A0A2V8GMY0 732-842 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.