DPCstruct | MC22015

Metacluster Properties and Pfam Annotations

Number of structural domains258
Mean domain length (aa)99 ± 13 aa
Standard deviation of domain lengths13.30
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.66
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)26.67
Pfam Score86.28
Assigned Pfam label(s) CL0023- CL0437- CL0329- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183AIW6 463-540 None
A0A0C2HAV4 489-592 None
A0A6H5L6M4 517-606 None
A0A6A4TBT0 711-828 None
A0A813CJS9 379-483 None
A0A640T5B4 166-261 None
A0A378VSB5 1-96 None
A0A3S3PF77 341-443 None
W4TNE1 61-167 None
B0DTC4 48-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.