DPCstruct | MC22012

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)284 ± 32 aa
Standard deviation of domain lengths32.46
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score71.83
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.13
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A150GH30 1-269 MRFFDDNTRSWWTPATGGANVPALNDLLAPFGLGLGDAVVHGTAAIAGMRVTLSYGVDVAKVPAGGWLHKATLSDAARKGSHPSSHG…
A0A7E4RVB3 185-414 MKKVKFFDENTRQWWMPDTGGANVPALNDLLSSWGIVLGDIVYDGDYTIGKQTVSYSSGSHIARFPSKGTVLSAKLTDQGNEILGGR…
A0A183KB78 54-383 None
A0A820XZW8 1-310 None
A0A444EQ09 213-470 None
A0A0L0BW23 126-456 None
F2UDW3 875-1158 None
A0A7S2F9U8 13-312 None
A0A072UCD4 157-478 None
A0A2G9PQC2 300-565 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.