DPCstruct | MC22004

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)240 ± 39 aa
Standard deviation of domain lengths38.87
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score76.56
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.19
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A835VW54 263-495 PAGGGSGGPPSVVAVSTGAQLVAALADPGKAGVLLLNDVALSDSDFSCLGLPLPRATNFTITGSQSSANPAIYPVLDLGFVKSKVRL…
A0A150G4G2 11-296 GLVRNISSGAEYAAAFNDPSVSTVLVTADLALSADDWDPYPSPVVLTRNVTLLGAYDEPTRWPVVDMAYVRAKMQLAPGVVFNASRL…
D8UAA5 114-410 None
D8U1K2 161-382 None
D8TMV9 33-271 None
A0A0D2M2X3 3-222 None
A8HM79 18-327 None
A8IU96 60-323 None
A0A150GMS0 3-181 None
D8UCA2 39-275 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.