DPCstruct | MC220

Metacluster Properties and Pfam Annotations

Number of structural domains33
Mean domain length (aa)250 ± 51 aa
Standard deviation of domain lengths50.63
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score79.10
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)35.28
Pfam Score100.00
Assigned Pfam label(s) CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T0PMP2 1-216 MLDKAPIYEVPASALTSPPQGTPRNPKKLMIEEPSYFIFNVAMSAAWGTTPPNVFMGGCRGDKNYPQPGTFEYNITNNICDSFPMYM…
A0A6A4DQZ9 433-679 GPSGYVRWMLDGDPLYEIPAETITTPPQGADTDLKNPRKIMIEEPLYLIFNVAMSSKWGAQPPNPRNPCRGDGTDPVANRICDSFPM…
A0A397F3F7 335-609 None
A0A067C1C0 1-164 None
K3X0H4 272-538 None
W2Q4Z8 573-843 None
V9DS61 64-339 None
A0A418AXL5 962-1237 None
A0A6G0QMG8 1-222 None
A0A482SU27 1-164 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.