DPCstruct | MC21999

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)201 ± 34 aa
Standard deviation of domain lengths34.34
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.24
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)26.47
Pfam Score97.92
Assigned Pfam label(s) CL0229- CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A286UV44 6-134 THISTLEGFSGPKLSQSVHREECTQCFDNQDTEDGVDICLSCFNGGCNDEKRHHAYNHANKTGHTFTFNIKRRPKPTLSKREDSDEP…
A0A150FZV0 1-184 MAAVDEAALARVRQYMRAVRMPSYHDKVYKDECMFSYDSPESPGGLYVNLATFQGFGEEYVGLDVQRSGGGLYLHLKHKRVPLPKAE…
A0A421JUL4 9-209 None
A0A1I7S1W3 11-193 None
A0A4R0RR84 1-218 None
A0A2V2XDL0 15-204 None
A0A367LCY3 574-777 None
A0A0B1PQJ1 564-771 None
A0A0R3Q7D0 13-193 None
A0A0N5CQF6 2-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.