DPCstruct | MC21993

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)107 ± 10 aa
Standard deviation of domain lengths9.96
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score86.42
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)41.88
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V3JVG9 1-97 MKVYLKNIKQTTSYLYTENQYFRFPPLVREFIAHWETLKSGGRAEGSIHWFTVTNSSNEGIGKGTYTTNEMFKLLGKQDVMPGVARA…
A0A158IWJ9 4-118 SEDAIDRAVRAQILRTQSQKGKRDIEKVYLQAANNVSNYIYVENQYFRFVPIAEKIKSAVAAQIKQGRSPDNPIYLFVITNSNDEGI…
A0A2X1REL8 1-97 None
J9KLD4 80-184 None
A0A4S2DRD2 1-96 None
A0A833QFM2 249-350 None
A0A336NHX5 10-133 None
A0A4R1UUU0 342-442 None
A0A496KVT7 478-600 None
A0A4R2T7V2 26-126 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.