DPCstruct | MC2199

Metacluster Properties and Pfam Annotations

Number of structural domains53
Mean domain length (aa)343 ± 66 aa
Standard deviation of domain lengths66.30
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.62
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)16.76
Pfam Score98.08
Assigned Pfam label(s) CL0286- PF20646

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G0WHG8 20-367 VTISKDTELPSSGSYSDSYNINEDATLAIADGTTVTGGTSASLSSNLDVDGNLCIGAESVTVTSSTITNNGNLVIYNGDSMTDGGTN…
X5ZPQ2 186-451 GTMTIGDGALLPLSGIINNSGLISLDSAGGDTLLQVIQHGVTLQGGGQILLSDSAANIISGTGPDATLVNVDNTIAGAGQLGGGMLS…
G0VJ51 24-393 None
H2B009 24-413 None
A0A5M6IRC1 1-347 None
A0A5M6J229 29-297 None
A0A4V1TTN1 33-302 None
A0A421JD66 13-381 None
A7WPK1 15-473 None
H2ARD8 21-289 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.