DPCstruct | MC21989

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)166 ± 16 aa
Standard deviation of domain lengths15.98
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score71.62
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.96
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6A3MUP2 380-545 LNVSVFKLLSWTIDEYRIAVREDDFFDSVERVLRDGKALGAAKTFYEDRVALVEKKFYVAGGSARMMFALTTTMAMDSLGKGLSAVD…
A0A7S0QDU5 10-174 LSPWTKEDYLEAVTNKAFFEQVKKMLDANNMLNAGTQEESLTPQELVESKFHFAGGSSKFMFDLSTEEVIVMIDAIVERCEDLFKYV…
A0A1V9YUK4 221-377 None
A0A081AZN0 115-294 None
G4ZQY4 55-201 None
A0A177WGX0 31-182 None
A0A485KIV1 10-179 None
A0A0W8CIC6 12-184 None
A0A833WP42 80-271 None
A0A329S023 2-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.