DPCstruct | MC21986

Metacluster Properties and Pfam Annotations

Number of structural domains290
Mean domain length (aa)399 ± 105 aa
Standard deviation of domain lengths104.87
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score86.97
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)22.31
Pfam Score99.79
Assigned Pfam label(s) CL0617- CL0337

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P5B2K5 3-267 VNWYGLLGKKFKDAFGHVGGAILGGMVGLKKPNNHGVPYSLTEEFVSVYRMHALLPDHLNLRDISAKPGPNKSPPLIRKIPMQNLIG…
A0A0U2KWQ1 33-380 THQIDGSNIYGPDEAWRRKLRSLRNGKLRSRMVNGEEWPLSVAEVPVAMRRLPNQRDEDLFALGHEFYTFSPGLIMVSTIWLREHNR…
H9G386 80-447 None
A0A2K6WMI1 845-1369 None
A0A445D0Q0 109-535 None
A0A226EKI3 532-1051 None
A0A3B4V9D5 94-381 None
A0A7R9A8L6 491-914 None
A0A810LES0 23-362 None
V4C5T3 65-567 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.