DPCstruct | MC2198

Metacluster Properties and Pfam Annotations

Number of structural domains110
Mean domain length (aa)170 ± 33 aa
Standard deviation of domain lengths32.94
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.64
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)18.84
Pfam Score52.75
Assigned Pfam label(s) CL0123- CL0036- CL0378

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R6UBC9 39-196 IDADVETDMYLYAVSYLKKHGFIQYEISNFAKPNAASLHNQMYWNYEDFCGIGCGASGKSGHIRYDNTRNLHTYLQKGSCPDIIELS…
R5JKY7 21-207 LAENDRLLRLIPDEDTDRKMYEATERLLISGGYNRYEISNYARPGYECRHNIKYWTLKEYIGFGIGASSFFNQRRFSNTQDMDEYIR…
A0A5N4D6H7 165-346 None
A0A4Y7JHW1 236-427 None
A0A4Y9LFH0 3-121 None
A0A6P5GHK0 243-476 None
A0A3C0U4T7 53-235 None
A0A7R9ZMU6 55-262 None
A0A6G3VIY2 5-132 None
U2SNY4 533-709 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.