DPCstruct | MC21969

Metacluster Properties and Pfam Annotations

Number of structural domains9
Mean domain length (aa)82 ± 6 aa
Standard deviation of domain lengths6.22
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.84
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)45.49
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446MU27 93-174 WLDLDLPEDWVLLDCRFVYLGAGRFCITKIFEFGEDEDTGHPTEMGAVISGVEVVHSENTLQMVKHKSKFYNYVKDTIACVF
A0A453H0Y9 42-121 WGDLSLPDDWEMMDCSMVYLGGGRFCVAKIFEFCLGDDRKGMGVISGLEVVRQGEPSKLVMVKHKSKLYKFTRGEIQCIL
A0A453SY97 1-80 None
A0A0E0JVH3 168-237 None
A0A0E0JT40 57-151 None
A0A0E0MC15 106-191 None
R7WGI7 185-268 None
A0A835BV83 447-530 None
A0A453H0Y3 114-193 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.