DPCstruct | MC21957

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)123 ± 14 aa
Standard deviation of domain lengths13.71
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score87.94
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)40.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I4N189 181-312 None
A0A4U3EZG7 97-200 None
A0A5A5RUU6 4-133 None
A0A2G0QDH7 503-628 None
A0A5W4L7V1 4-113 None
A0A2V2A0Q5 25-145 None
A0A2D0KGX0 150-279 None
A0A423ISQ2 479-612 None
A0A0F6W4H1 489-594 None
A0A5E7S531 1-107 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.