DPCstruct | MC21954

Metacluster Properties and Pfam Annotations

Number of structural domains420
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths45.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)20.18
Pfam Score99.13
Assigned Pfam label(s) CL0125- PF20108- CL0716- CL0366- PF05634

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A448IWN9 4-187 None
A0A6N2KWF4 6-232 None
A0A2K0TYV9 7-199 None
A0A7N9D8W8 763-958 None
A0A2D4BUG3 455-820 None
A0A061ASA0 40-291 None
A0A1V9X2A8 29-229 None
A0A4T0FI09 353-623 None
A0A4T0FHV1 657-918 None
A0A399X3Z7 16-233 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.