DPCstruct | MC21954

Metacluster Properties and Pfam Annotations

Number of structural domains420
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths45.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)20.18
Pfam Score99.13
Assigned Pfam label(s) CL0125- PF20108- CL0716- CL0366- PF05634

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A176VS93 173-355 None
A0A0V0H2F0 3-135 None
A0A2T5VMP2 7-223 None
A0A087SQC0 2-272 None
A0A0D1CQG6 142-392 None
S3D4A7 458-726 None
A0A2P6UZI7 124-385 None
A0A7D3U2W9 11-190 None
G7E2Q5 1-283 None
I1MDI7 9-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.