DPCstruct | MC21954

Metacluster Properties and Pfam Annotations

Number of structural domains420
Mean domain length (aa)214 ± 46 aa
Standard deviation of domain lengths45.76
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score85.62
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.54
Mean intra-cluster sequence similarity (%)20.18
Pfam Score99.13
Assigned Pfam label(s) CL0125- PF20108- CL0716- CL0366- PF05634

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
D0NA73 32-217 None
R1EIZ5 4-190 None
A0A4S8ID58 58-228 None
A0A183Q9R5 316-532 None
A0A7R9CQ42 34-265 None
E4Y9W3 8-212 None
A0A7I8VP30 33-267 None
A0A524ANQ5 7-293 None
A0A814D2B8 372-611 None
A0A438GBA0 3-194 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.