DPCstruct | MC21934

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)337 ± 44 aa
Standard deviation of domain lengths43.54
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score74.78
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.22
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W2JVA4 419-736 GNREGVEHLLTYTSASSALHRALSAAAPGELRAVAAAWSRKAGLSIDWPGMNAELNALLQSSLAPWSGFYLDSSRRMSLSLFSRMKN…
A0A7D9JMM1 194-517 NSNNAARAAAIELLTSNSFCKSYADEMKKYVHDPDLDTKLTAFLELHGFKTTPDAVQNALQELRESSLLPWRQVYHTSVGILEIRCK…
A0A0P7AQ33 1-404 None
A0A066YLN8 385-680 None
S3IW50 1-390 None
A0A519H2S8 1-370 None
T0KES9 6-418 None
A8YDG8 305-596 None
A0A2W4SPG2 4-302 None
W1IMK7 574-903 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.