DPCstruct | MC21909

Metacluster Properties and Pfam Annotations

Number of structural domains296
Mean domain length (aa)185 ± 36 aa
Standard deviation of domain lengths36.32
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score71.53
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.35
Pfam Score97.39
Assigned Pfam label(s) PF12428- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z7C6A9 2-143 None
A0A7S4VTP1 173-322 None
A0A446S0U2 1-145 None
A0A3Q0CJ52 18-217 None
A0A067F8H9 39-256 None
A0A1Y1INY0 243-412 None
A0A1Y1IKK6 69-259 None
A0A4V3SA37 295-506 None
A0A5D2R6S0 2-169 None
A0A1D6KSS0 212-399 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.