DPCstruct | MC21909

Metacluster Properties and Pfam Annotations

Number of structural domains296
Mean domain length (aa)185 ± 36 aa
Standard deviation of domain lengths36.32
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score71.53
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.35
Pfam Score97.39
Assigned Pfam label(s) PF12428- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S4EPH2 240-446 None
A0A1S3DV84 67-266 None
A0A6P7MDL1 1-177 None
W6V3M2 66-258 None
A0A6P5A2I4 415-619 None
A0A0E0CN39 87-251 None
A0A0G4FIM3 1-172 None
A0A0G4FI58 48-222 None
A0A1D1UQN5 240-443 None
A0A183A752 166-390 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.