DPCstruct | MC21909

Metacluster Properties and Pfam Annotations

Number of structural domains296
Mean domain length (aa)185 ± 36 aa
Standard deviation of domain lengths36.32
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score71.53
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.33
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)20.35
Pfam Score97.39
Assigned Pfam label(s) PF12428- CL0229

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4RSF7 25-133 GDLCRICQMSAVAPGNLLVVPCSCTGSLQYVHQDCMRRWLEAKIKSGAELSAVLHCELCKQLLRFEVEGFDIHQLYQEHSANQAQSD…
A0A6P6XM57 7-185 KMISNNYSVGVGGGNHKKEKPICNICRQEESFKNLISPCDCKGTGGFVHFDCIKRWIETSGNDHCKACNVIYRKLKMRKKSGSFGKF…
A0A7S2SW95 2-181 None
A0A6S7FEX8 207-408 None
A0A7R9KCT9 4-148 None
A0A0N0P944 1-301 None
A0A1D2NJ48 324-490 None
A0A7R9NWQ4 613-792 None
A0A5P1FM83 796-983 None
A0A2C9JXR9 276-479 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.