DPCstruct | MC2190

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)119 ± 8 aa
Standard deviation of domain lengths8.18
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score82.74
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)20.39
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
P22902 5-122 MIDALNIATMPIADKVHRHMLASYYALQLDALQAEAKRLGYFFAQADTAATMPPVLADCLAWAVEYRRRCYLYPNCPESWERHTADS…
A0A212BGW0 1-140 MNLPVNIADLAIADRVNRRVNSYFFANHLKVIQKVAAESGYRFVQCPPEEEIGRLPADLERAMEEGLAKARADYTLKKASAEQKQRW…
A0A7U4Q3C9 1-114 None
A0A2P8L6A5 79-194 None
A0A6H3AQW8 16-135 None
A0A0T9R1Q8 152-275 None
A0A0A3Z3W0 17-129 None
E3HY76 257-365 None
A0A3A3Z845 63-176 None
A0A5J6W9K2 67-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.