DPCstruct | MC2187

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)155 ± 6 aa
Standard deviation of domain lengths5.94
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score77.51
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)27.39
Pfam Score100.00
Assigned Pfam label(s) PF07849

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I1AAT2 1-143 MEISEETIRKRNLEEIKKAVSDHKEAVLKGIDFLETLNKSGTLDMVDALIKHREDALENVMREINKPQYAATLENLPKLLILIGELN…
A0A150JNL9 1-155 MAKAIRQIKQVDPAPEEWQAASMSAVVKAAAENGESLIKLLEIIKQLDGMGVLNAMEGLLQNRVDVAEIALGQLNQPAMYHVIKNGM…
A0A7C8KPG6 1-160 None
T0C9Q7 1-157 None
E7RD13 1-158 None
A0A0Q5LBV4 1-149 None
A0A223D199 1-159 None
A0A837YXX2 1-149 None
A0A1N7KTK6 1-160 None
A0A4P6UVI6 1-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.