DPCstruct | MC21854

Metacluster Properties and Pfam Annotations

Number of structural domains103
Mean domain length (aa)201 ± 48 aa
Standard deviation of domain lengths47.71
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score85.16
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)20.61
Pfam Score81.57
Assigned Pfam label(s) CL0286- CL0279- PF02245

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3Y3T3 329-549 MRVKEGEADYRYFPEPDIPPLRLDADLLSAWKAALVELPAAKRARYVRDLGLDAEQARVLTDDQQTAAYFEAAVAAGGAGCAPVEVC…
A0A7J4B288 2-147 LRELEKQTNKELAVQLLHSTYLGAYEKAVGMGIDPKVAAVTFVSTLKTIAREGLPAYNIDPDKVIEVLKKYAEGKITKKAVEEVLRE…
K2S685 62-318 None
A0A482WU22 220-451 None
A0A3T0Y475 792-1005 None
A0A1R0GR32 1-128 None
A0A0G0V2N4 202-436 None
F4Q6Y1 2-146 None
A0A4Y7L8Y3 347-486 None
A0A832ZXA5 208-464 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.