DPCstruct | MC21845

Metacluster Properties and Pfam Annotations

Number of structural domains30
Mean domain length (aa)160 ± 25 aa
Standard deviation of domain lengths24.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score75.14
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)26.75
Pfam Score100.00
Assigned Pfam label(s) CL0110

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X0MHD0 48-219 RYLLVGLLALVGLHWLALFMSPSYAASASLEAIAFKSGLGSDGSPSSWHDSSTTNLDDLTSVGGTGLAPFESLDPELNAITFVILAR…
A0A1Y3MXI6 8-119 LLTIVNFLAIFVLYRFLFKVFNKEPKEIDYSYLYNKNETDIKACIFILCQDKDQEKLIKTIHELEATFPHKYPYILLNDVPFSDTFK…
E3RU58 1-157 None
A0A0N0NJP0 27-206 None
A0A370TLK4 1-149 None
A0A146IMZ2 342-560 None
Q2GND4 807-920 None
A0A6A5WA99 2-193 None
A0A1E4RI66 282-456 None
A0A5Q7YAG3 12-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.