DPCstruct | MC21811

Metacluster Properties and Pfam Annotations

Number of structural domains189
Mean domain length (aa)82 ± 23 aa
Standard deviation of domain lengths22.59
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score70.14
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.70
Pfam Score98.98
Assigned Pfam label(s) CL0083- CL0199- CL0004- PF20481

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067CBS0 64-148 ADHVGLWAQCGGKDFTGSRACPAGAACVTVNEHYAQCQATATDAAHLPTYAQCGGSNNGFDANGKACRDEDTCFRFNAHFWQCLP
A0A2D4CFJ4 10-94 MVAMRFDYQAYGVVATGSSTLPLLQCEPGFVCEAVNEFYFQCIRGGPAVALWGQCGGLGYTGSTYCASGARCHYYTRWYSQCLPA
A0A397F642 118-196 None
A0A820N782 130-201 None
A0A1Q5U7B0 244-310 None
A0A4Q2DNC1 203-262 None
A0A4Q2DQG3 885-958 None
A0A6P8AZ97 333-390 None
A0A5C3LL12 1-84 None
A0A5C3LS24 10-82 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.