DPCstruct | MC21799

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)481 ± 89 aa
Standard deviation of domain lengths89.37
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.63
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)24.55
Pfam Score80.02
Assigned Pfam label(s) CL0070- PF21078- CL0063- PF21079

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0U1DPJ4 1-477 MHFTVNEAGARAEVRWPGPPPLLAEVCAMFEHFGLRVASYQLTDTGHHYEFGTLPLPRPTLELIARAFEAATAGHWQTDRYAALIPS…
A0A858Q8P5 36-576 SLPGAWVFPPEYRSRIPPAAALRDAIRLETVVRTGADTADLWRPSPCFGDPHHRLRIYSPVEQDLDRVMPFLQNLHLRIIDQIQFRL…
A0A1V9ZWE0 80-594 None
A0A8A5WQT7 472-936 None
A0A1G3R0N2 1-456 None
A0A829Q4S5 17-531 None
A0A812QVV0 2-531 None
A0A2N1TGU3 190-905 None
A0A401GRF2 8-414 None
A0A7Y2YV14 140-676 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.