DPCstruct | MC21793

Metacluster Properties and Pfam Annotations

Number of structural domains1329
Mean domain length (aa)77 ± 12 aa
Standard deviation of domain lengths11.66
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score87.27
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)24.02
Pfam Score99.15
Assigned Pfam label(s) CL0023- PF14239- PF00926- CL0263

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C8P1J1 60-144 LYSQRYNAKKKALPYDLSADELDDIYSQFNYSCALTGTSKNLHHEHFICIDTGHMGTTYGNIIPLDGSLNISKNNKNPFEWIKDF
A0A359BF23 18-82 DAKRMWREEIKRRDGYRCVYCGSTDNLTIDHVVPQCKGGPTDAANCRTACLACNQAKGSLSLNDF
A0A6N0LVQ3 9-91 None
A0A496SU11 184-256 None
A0A843AW91 43-102 None
A0A7C1Q0C4 122-197 None
A0A6G2HIW3 3-78 None
A0A7R8XLD4 5-80 None
A0A1M7IWG6 91-180 None
A0A350XTX7 226-308 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.