DPCstruct | MC21781

Metacluster Properties and Pfam Annotations

Number of structural domains4
Mean domain length (aa)52 ± 2 aa
Standard deviation of domain lengths2.17
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score87.77
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)38.03
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7E4RJL8 1-52 MEISSFRKATLMGSPCIISEQCWQKVANSVCHAGVCRCSKGYLQYRRHTCVP
A0A6L2Q2M1 1-51 MYSSTPAAIGSPCTADDRCNTFIPNGVCRDGACACADGYVAHPTSTTSCLP
A0A182JFQ8 25-73 None
A0A182P0X2 1-55 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.