DPCstruct | MC21766

Metacluster Properties and Pfam Annotations

Number of structural domains81
Mean domain length (aa)155 ± 29 aa
Standard deviation of domain lengths29.34
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.02
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)19.43
Pfam Score98.84
Assigned Pfam label(s) PF08617- PF04045

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A218NLL0 12-153 LLKHSFAFRLYKRKSSFEIIFDQADRFNKQNAKKYEFVLLLKPYLSDDYPELVFAYINACLSFKNKTNRSSSIPLEMLIYLSGAKSI…
A0A2C5WTZ6 5-170 LETIALEHLPATHTLHMVLFQDVKNAEFLHKQLLARNAEFEYALVDAGIATSRHQIMAAVYKAASSDLNGTLRTPNVHSEIVNSLNP…
A0A7M4EUG4 1-117 None
A0A2A2KLA4 26-138 None
A0A109FMY2 261-422 None
L0AZK8 29-183 None
A0A482VBL3 283-437 None
A0A146HJ47 4-196 None
A0A6A6LCF9 159-311 None
A0A1X6PHL4 11-116 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.