DPCstruct | MC21764

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)243 ± 49 aa
Standard deviation of domain lengths48.56
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score76.82
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)38.75
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0A9VE74 1-162 MEDAKDPCFWSRICMHSIAKLSKEATTFRRVMESLFRHFDDTNSWLSKNGLALCVLLDMQMFMENSGQNINLTISILVTHLGHKAVL…
A0A5D3CGP5 1-230 MGEFSNISAEFDNVISVVLDNYGDVESTSRQDTQDATALVTHPREHITRMCSWRMIVTEKGEIIVSLEDAQNPQFWSRVCLRNIAKL…
A0A5D2HWY4 219-416 None
A0A2U1M0V6 418-649 None
A0A5N5FB46 1-180 None
A0A1D6MMM9 3-252 None
A0A7J0F332 168-454 None
A0A453SPI0 38-280 None
A0A445IMJ6 168-469 None
A0A2I0I9M4 47-299 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.