DPCstruct | MC21746

Metacluster Properties and Pfam Annotations

Number of structural domains88
Mean domain length (aa)136 ± 23 aa
Standard deviation of domain lengths23.18
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.74
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)32.16
Pfam Score87.31
Assigned Pfam label(s) CL0376- PF12631- CL0329- CL0289

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4D9F445 2-97 AVIRTSGSASGAALRSLTGQQELPWPRAVTLRRIHDPSSMETLDRGLVIWFPGPHSFTGEDCSELHVHGGPAVVGSVLQALGLLPGL…
A0A517P6E4 4-116 RPTAALLTPPGRGAVAVIRVVGPPTLCDAAFAAANGRPVSAQPLNRVAFGRWGRDESERRPGEELIVVRTAADETEIHGHGGRAAID…
A0A1L8ZDU3 2-114 None
A0A836ASJ3 2-124 None
A0A5M9N106 1-151 None
A0A060ZIK5 56-156 None
A0A1G1DJ46 5-157 None
A0A7V4J2E5 1-144 None
A0A7V8VGQ9 3-112 None
A0A388KNV0 643-797 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.