DPCstruct | MC217

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)287 ± 24 aa
Standard deviation of domain lengths24.49
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score80.74
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)18.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A423JUU5 254-523 LATSVEGIQMELNHQEPALITGVDSQWVRERADALTDHLKALVDSTQRCAPLLNVAHPRGLRWFVSSSGRLIDTGNVLHPDSTVAVG…
G2H2B9 4-287 NGCILDIKLQNDAFIATLFGCTPRFSDADDRSRAGMMINRGELERALTTFCSLYSCPEIIMIRLKNRGYGWFHPASSALFTLPIEAS…
A0A2R7RJH1 740-1009 None
A0A7Y4A1R9 50-303 None
A0A6L2ZQM4 2-250 None
A0A6L2ZMS7 644-930 None
A0A2U8I5X1 823-1167 None
A0A2U8I2F3 303-604 None
E0WUM3 70-382 None
A0A2R7KGN9 967-1245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.