DPCstruct | MC21682

Metacluster Properties and Pfam Annotations

Number of structural domains333
Mean domain length (aa)240 ± 47 aa
Standard deviation of domain lengths46.98
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score85.10
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.37
Mean intra-cluster sequence similarity (%)11.73
Pfam Score95.48
Assigned Pfam label(s) PF00082- PF02464- CL0422- CL0268

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5E4PIL1 67-320 VTISQYPYSAAVSTMSVRVPDFSNIKVNGDFQVQIFGTYGSNSVYVYGPNEAVRGTIIEVRGNTLCVDQARKVTGNMRNVIVRIGVN…
F7YXU3 3-222 KFSLDFSDVRKLIVKSLSSDVQISSSQMEYSVTGPEKDLLIEKKNGTLEISVTGRGMIPIFNHDSTPISLTIPTQLDEIIVTTISGD…
A0A136LGY9 15-201 None
A0A2R3MYE8 39-338 None
A0A0Q0XJ53 29-185 None
A0A7D7KYQ7 58-261 None
A0A4Y4D957 98-320 None
A0A2G6H4V3 22-230 None
A0A7Y4XP72 296-488 None
A0A7C0W8I8 22-299 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.