DPCstruct | MC21648

Metacluster Properties and Pfam Annotations

Number of structural domains266
Mean domain length (aa)182 ± 34 aa
Standard deviation of domain lengths34.09
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score87.56
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.26
Pfam Score71.00
Assigned Pfam label(s) CL0123- CL0578- CL0260- PF20217

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1V6CWG3 7-196 NQQKALKYAREHGPFRPRDVAGIGVHPEDIRRLCRKGLLVRAGRGLYGLADAEPTTNQTLIEACKRVPQGVVCLLSALRFHGIGMQL…
A0A7J2VWQ2 3-183 ETIILEKFSSMPVFSLADISQITKSKAYAKFLISSLLKKGKIKKIKRDLYTLHEDAFLVATFIIRPSYISSISALSFYGDISQIPNE…
A0A367U760 8-184 None
A0A7V9GF52 15-197 None
A0A7V9EVI1 2-151 None
A0A812P0I7 7-216 None
D3LKL3 19-222 None
A0A430AWY6 23-230 None
A0A2W5KBV5 5-153 None
A0A6B1AFN5 17-226 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.