DPCstruct | MC21642

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)209 ± 44 aa
Standard deviation of domain lengths43.68
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score87.76
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)22.49
Pfam Score83.78
Assigned Pfam label(s) CL0020- CL0126- PF03105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4RRI8 52-184 IGFVKAYIEKFAYSTATTEEWKAYLFEYFKDKADVLQAVDWKAWIYSPGMPPVKLQYDTTLADDCSALATRWSQAKDADLASFSADD…
A0A1J9R1S5 757-969 ENLIGKAKFDKFIPHYFTKYKELSLDSYEFKSSMLHFFSNDSEAHALLTSLDWDKWFYSPGLPPKPDLDTSLVDVVYDLAEKWRTAP…
A0A0V0QJ06 595-880 None
A0A7M5WKU3 801-1114 None
A0A498KNH9 648-854 None
A0A7J6PIY8 1019-1237 None
A0A4Y7MJI3 148-334 None
A0A662Y927 91-319 None
A0A2I4ALN6 12-196 None
A0A4Q4YEQ6 604-819 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.