DPCstruct | MC21599

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)351 ± 74 aa
Standard deviation of domain lengths74.37
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score89.39
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)28.62
Pfam Score95.45
Assigned Pfam label(s) PF13660- PF05161

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D6KWG5 20-391 IINSGLQSINTEKIIRNNIKLKNNILNIKNKKINLKRYKRIFVIGFGKASSLMGKEIERILGSRINNGIIISTKNIQLKRINVIKGT…
A0A1B3WMU6 147-487 VIDSILDQVRLAIAPDQLLYRIAQETETGYRFGDIDVDFSLYRTVNVLAIGKAARRMASALGNLIEERIDAGLIVSKTPFEMGEFPP…
A0A7W6C6G1 6-291 None
A0A0G1ZNZ8 550-956 None
A0A1F8RI35 1-395 None
A0A0L7QNQ2 2-395 None
A0A6L5D8K4 45-270 None
A0A810Q683 18-413 None
A6TL35 336-702 None
A0A136KYL4 39-329 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.