DPCstruct | MC21523

Metacluster Properties and Pfam Annotations

Number of structural domains285
Mean domain length (aa)259 ± 51 aa
Standard deviation of domain lengths50.65
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score84.34
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)13.24
Pfam Score38.26
Assigned Pfam label(s) CL0276- PF13675- CL0161- CL0681- CL0183

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7U5W2J4 5-214 KIPVRLAIGLGAVASIGIAIALLGAVALRSLTANLQEITADRMAKVAQFTELKDNLNAIARYARNIVISGNTAVQREEKRKLAELRE…
B8GFV2 7-249 LMLSFSVLAVVFLIAGVIISANVTGMNALDKRISTDLTINQQAIAYQNAARDVQTGTFLYLQGETGMGNQMINEGELQMVKSRLALN…
A0A5C8KA58 27-248 None
A0A844YT43 15-238 None
A0A2G7GCY3 198-418 None
A0A244C0B5 3-189 None
A0A351I9V4 3-276 None
A0A447PXV1 2-158 None
A0A161R7L8 5-305 None
J3C4C4 5-210 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.