DPCstruct | MC21497

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)246 ± 50 aa
Standard deviation of domain lengths49.85
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.33
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)21.78
Pfam Score100.00
Assigned Pfam label(s) PF00460

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A455UZD8 2-142 QNFFSALEDLASAPSDPAARQGVLGTADTLTAQFRSFDGYLQDLQSGVNGQIKDEITQINNTTSQIANINREIALSRAQLGEAPNSL…
A0A455U2Z7 4-269 FSIGLSGLNAAQNALNTSSNNISNVYTPGYNRELAQLGEGRVGGGVRVNDIERQFNTYVADQLNSAKTQSSALNTYYNQVSQIDNLL…
N1ZDT9 11-331 None
A0A1I8APY8 1-191 None
A0A015KSF0 16-210 None
A0A258D969 1-227 None
A0A7X7Y2P5 1-279 None
A0A7C3AS12 3-213 None
A0A0B0I5M6 2-124 None
K6UMD5 152-369 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.