DPCstruct | MC21482

Metacluster Properties and Pfam Annotations

Number of structural domains326
Mean domain length (aa)94 ± 16 aa
Standard deviation of domain lengths16.36
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score80.40
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)19.02
Pfam Score82.62
Assigned Pfam label(s) CL0063- CL0182- CL0582- CL0030- CL0064

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C0ZCS4 7-80 AEETVETVEVSPDSPVAGKTLREAGIAEETGMWVLYIRRGGRWLKPKPNTRLLPGDLVVASGYSEGEEDFKKLL
A0A5B7TF51 10-96 LIDYIERFKNISPFTLIEISIKEPSWVIGKNLDEVKFWKNTGATIIAYREGEKIVVSPGPDYRFKAGDIIVVIGSSDVYERVCNFIY
A0A177KUH8 289-374 None
A0A2R6CVZ5 337-415 None
A0A352ACL5 477-594 None
A0A3D0I349 63-140 None
U1QZZ8 66-161 None
A0A251WN32 9-90 None
A0A5P9P9Q7 173-278 None
A0A847A6H9 68-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.